Resveratrol is a major phytoalexin. It can inhibit cancer, lower blood lipids, prevent cardiovascular disease, anti-oxidation and slow down aging. It has been called as a green anti-cancer drug after paclitaxel. Resveratrol is extracted primarily from grape skins and polygonum cuspidatum plant. In recent years, Europe and the United States have developed it into a health food. There are tablets, capsules and oral liquid dosage forms.
There are a dozen of Chinese manufacturers producing resveratrol natural pure extract. Most of their products are for export. At present, the market price of the product in about 18,000 to 20,000 RMB / kg. Currently, in Europe and the United States has approved the listing of resveratrol high-end finished products (including drugs and health products) for almost thousand kinds, about 200 million global users of the goods, and an average annual growth rate of 50 million. Resveratrol preparations It is estimated that sales in the next eight years to reach 500 million to 800 million U.S. dollars, will form a very huge industry. Preparation market expansion will further promote the growth of its demand for raw materials.
In 2003, China adopted a large-scale medicinal plant cell culture artificial technology, it solved major technological bottlenecks for large-scale extraction of resveratrol. The unique Chinese herbal medicine Polygonum cuspidatum resveratrol content is also very high, has been using 95% ethanol reflux extraction, or 70% acetone extract, process complexity, high cost of production. China’s first to develop a microbial fermentation enzyme technology, one-time extraction of crude content increased by 8 times than the traditional process, but also shortens the production cycle.
At present, many research institutions and universities are stepping up studies of resveratrol synthesis process, China has developed a five-step extraction of resveratrol process, the yield up more than 20%. In addition, the process of companies to develop successful two-step method to extract resveratrol and irinotecan. Synthesis process is expected to break the bottleneck of the plant material, reduce production costs to achieve large-scale production.
Due to technology limitations, the purity of resveratrol production is poor in China. There are used or exported in the form of raw material mixture. The products added value is sharply. For example, 95% purity resveratrol has a huge market demand in the field of pharmaceuticals, biological products, and health functional food (the total value of Chinese medicines and health functions food market is up to $ 12.2 billion), The price in international market is about $ 11,000 / kg with a good economic value. Only a few in China can produce it, there is a big gap in the market.